Dental organ

Result: During cap stage and early bell stage, the expression of MMP-20 mRNA was negative in enamel organ, dental papilla and dental sac and that of TIMP-1 mRNA could be observed in dental papilla;

结果：帽状期及钟状早期，成釉器、牙乳头及牙囊MMP-20mRNA表达阴性；TIMP-1mRNA在牙乳头表达；

It is a fiber network structure which is formed by dental epithelial and dental mesenchymal inducing by the signal of dental epithelial organ. But dental epithelial organ gradually shrinks away as the complete maturation of tooth in adult body.

它是牙源性上皮组织的诱导下由间充质和上皮共同形成的纤维网状结构，但在成体情况下，上皮来源的组织随着牙齿的发育成熟逐渐萎缩消失。

It is so crucial to find a way to imitate the function which is induced by dental epithelial organ that can be beneficial for the formation of basement membrane and dentin.

因此，找到一种能够仿照上皮发挥诱导作用的途径对于基底膜的形成和牙本质的再生就显得十分关键。